Version 5.4
Mus musculus Gene: Ccng1
Summary
InnateDB Gene IDBG-163399.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccng1
Gene Name cyclin G1
Synonyms AI314029
Species Mus musculus
Ensembl Gene ENSMUSG00000020326
Encoded Proteins
IDBP-163401
cyclin G1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113328:
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:40748552-40755311
Strand Reverse strand
Band A5
Transcripts
ENSMUST00000020576 ENSMUSP00000020576
ENSMUST00000151359
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0006949 syncytium formation
GO:0007067 mitotic nuclear division
GO:0007095 mitotic G2 DNA damage checkpoint
GO:0007420 brain development
GO:0010243 response to organonitrogen compound
GO:0016049 cell growth
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0030425 dendrite
GO:0043025 neuronal cell body
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000113328
View Gene Order
ENSBTAG00000006607
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04115
p53 signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04115
p53 signaling pathway pathway
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
p53regulationpathway
p53 pathway
Cross-References
SwissProt P51945
TrEMBL Q5NC86 Q6LC40
UniProt Splice Variant
Entrez Gene 12450
UniGene Mm.2103 Mm.395921
RefSeq NM_009831
OMIM
CCDS CCDS24550
HPRD
IMGT
MGI ID MGI:102890
MGI Symbol Ccng1
EMBL AB005559 AK143114 AK147026 AK159831 AK167486 CH466609 L49507 U87998 Z37110
GenPept AAB83957 AAC42082 BAA24492 BAE25273 BAE27619 BAE35410 BAE39566 CAA85474 EDL32333
RNA Seq Atlas 12450

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca