Version 5.4
Mus musculus Gene: Ddt
Summary
InnateDB Gene IDBG-163706.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddt
Gene Name D-dopachrome tautomerase
Synonyms C78655
Species Mus musculus
Ensembl Gene ENSMUSG00000001666
Encoded Proteins
IDBP-163708
D-dopachrome tautomerase
IDBP-626911
D-dopachrome tautomerase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099977:
D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:75771230-75773414
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000001716 ENSMUSP00000001716
ENSMUST00000172820 ENSMUSP00000134561
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0033981 D-dopachrome decarboxylase activity
Biological Process
GO:0042438 melanin biosynthetic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000099977
View Gene Order
ENSBTAG00000022027
Not yet available
Cross-References
SwissProt
TrEMBL G3UZN1
UniProt Splice Variant
Entrez Gene 13202
UniGene
RefSeq NM_010027
OMIM
CCDS CCDS23930
HPRD
IMGT
MGI ID MGI:1298381
MGI Symbol Ddt
EMBL AC142499
GenPept
RNA Seq Atlas 13202

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca