Version 5.4
Mus musculus Gene: Cks1b
Summary
InnateDB Gene IDBG-164476.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cks1b
Gene Name CDC28 protein kinase 1b
Synonyms 2410005G18Rik; 2610005D03Rik; AA407784; Cks1; sid1334
Species Mus musculus
Ensembl Gene ENSMUSG00000028044
Encoded Proteins
IDBP-164478
CDC28 protein kinase 1b
IDBP-266713
CDC28 protein kinase 1b
IDBP-787774
CDC28 protein kinase 1b
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173207:
CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:89415472-89418383
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000029679 ENSMUSP00000029679
ENSMUST00000107422 ENSMUSP00000103045
ENSMUST00000183484 ENSMUSP00000138900
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0007049 cell cycle
GO:0045859 regulation of protein kinase activity
GO:0051301 cell division
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000173207
View Gene Order
ENSBTAG00000024476
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_260005
G1 Phase pathway
REACT_223647
Cyclin A:Cdk2-associated events at S phase entry pathway
REACT_188804
Cell Cycle pathway
REACT_258573
Cyclin D associated events in G1 pathway
REACT_253002
G1/S Transition pathway
REACT_250573
Mitotic G1-G1/S phases pathway
REACT_245868
Cyclin E associated events during G1/S transition pathway
REACT_220647
SCF(Skp2)-mediated degradation of p27/p21 pathway
REACT_253623
S Phase pathway
KEGG
mmu05222
Small cell lung cancer pathway
mmu05200
Pathways in cancer pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_9003
SCF(Skp2)-mediated degradation of p27/p21 pathway
REACT_9029
Cyclin A:Cdk2-associated events at S phase entry pathway
REACT_1574
Cyclin E associated events during G1/S transition pathway
REACT_821
Cyclin D associated events in G1 pathway
REACT_1590
G1 Phase pathway
REACT_21267
Mitotic G1-G1/S phases pathway
REACT_899
S Phase pathway
REACT_1783
G1/S Transition pathway
REACT_115566
Cell Cycle pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
hsa05222
Small cell lung cancer pathway
hsa05200
Pathways in cancer pathway
INOH
PID NCI
foxm1pathway
FOXM1 transcription factor network
Cross-References
SwissProt
TrEMBL V9GWZ0
UniProt Splice Variant
Entrez Gene 54124
UniGene
RefSeq NM_016904 XM_006519761 XM_006543132
OMIM
CCDS CCDS38493
HPRD
IMGT
MGI ID MGI:1889208
MGI Symbol Cks1b
EMBL AC171273
GenPept
RNA Seq Atlas 102640775 54124

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca