Mus musculus Gene: U2af1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-164737.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | U2af1 | ||||||||||||||||||||||
Gene Name | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 | ||||||||||||||||||||||
Synonyms | 2010107D16Rik; 35kDa | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000061613 | ||||||||||||||||||||||
Encoded Proteins |
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160201:
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 17:31647082-31658754 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | B1 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 91 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
mRNA 3'-end processing pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
RNA Polymerase II Transcription Termination pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
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KEGG |
Spliceosome pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
mRNA 3'-end processing pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
Gene Expression pathway
RNA Polymerase II Transcription pathway
Cleavage of Growing Transcript in the Termination Region pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing pathway
mRNA 3'-end processing pathway
Transport of Mature Transcript to Cytoplasm pathway
RNA Polymerase II Transcription Termination pathway
Gene Expression pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
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KEGG |
Spliceosome pathway
Shigellosis pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | |||||||||||||||||||||||
RefSeq | NM_001163769 NM_024187 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS28611 CCDS50055 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||