Mus musculus Gene: Brd4
Summary
InnateDB Gene IDBG-165269.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brd4
Gene Name bromodomain containing 4
Synonyms Brd5; HUNK1; MCAP; WI-11513;
Species Mus musculus
Ensembl Gene ENSMUSG00000024002
Encoded Proteins
bromodomain containing 4
bromodomain containing 4
bromodomain containing 4
bromodomain containing 4
bromodomain containing 4
bromodomain containing 4
bromodomain containing 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene was temporarily named bromodomain-containing 5 (Brd5) and was renamed bromodomain-containing 4 (Brd4). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:32196274-32284722
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000003726 ENSMUSP00000003726
ENSMUST00000114475 ENSMUSP00000110119
ENSMUST00000121285 ENSMUSP00000113070
ENSMUST00000119123 ENSMUSP00000113197
ENSMUST00000120276 ENSMUSP00000112474
ENSMUST00000127893 ENSMUSP00000115163
ENSMUST00000125899 ENSMUSP00000115277
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 9 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0070577 lysine-acetylated histone binding
Biological Process
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0001833 inner cell mass cell proliferation
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0007059 chromosome segregation
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043388 positive regulation of DNA binding
GO:0043983 histone H4-K12 acetylation
GO:0044154 histone H3-K14 acetylation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050727 regulation of inflammatory response
GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:2000002 negative regulation of DNA damage checkpoint
Cellular Component
GO:0000790 nuclear chromatin
GO:0000794 condensed nuclear chromosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0008024 positive transcription elongation factor complex b
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
TSLP pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.253518 Mm.395253
RefSeq NM_001286630 NM_020508 NM_198094 XM_006524683 XM_006524684 XM_006524685 XM_006524686 XM_006524687 XM_006524688 XM_006524689 XM_006524692 XM_006524694 XM_006524695 XM_006524696
OMIM
CCDS CCDS37554 CCDS50057 CCDS70784
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas