InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp8b2

Summary

InnateDB Gene

IDBG-165272.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp8b2

Gene Name

ATPase, class I, type 8B, member 2

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000060671

Encoded Proteins

IDBP-165274

ATPase, class I, type 8B, member 2

IDBP-266753

ATPase, class I, type 8B, member 2

IDBP-622145

ATPase, class I, type 8B, member 2

IDBP-622146

ATPase, class I, type 8B, member 2

IDBP-622147

ATPase, class I, type 8B, member 2

IDBP-622148

ATPase, class I, type 8B, member 2

IDBP-622152

ATPase, class I, type 8B, member 2

IDBP-622154

ATPase, class I, type 8B, member 2

IDBP-622156

ATPase, class I, type 8B, member 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143515:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:89939481-89963508

Strand

Reverse strand

Band

Transcripts

ENSMUST00000069805	ENSMUSP00000063384
ENSMUST00000107396	ENSMUSP00000103019
ENSMUST00000163354
ENSMUST00000166347
ENSMUST00000168276	ENSMUSP00000128423
ENSMUST00000166502	ENSMUSP00000132201
ENSMUST00000163152
ENSMUST00000171941	ENSMUSP00000130545
ENSMUST00000167442
ENSMUST00000170324
ENSMUST00000170739	ENSMUSP00000127720
ENSMUST00000167257
ENSMUST00000171818
ENSMUST00000166705
ENSMUST00000170696	ENSMUSP00000126142
ENSMUST00000168880	ENSMUSP00000128726
ENSMUST00000171422	ENSMUSP00000129641

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0004012	phospholipid-translocating ATPase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0019829	cation-transporting ATPase activity
GO:0046872	metal ion binding

Biological Process

GO:0006812	cation transport
GO:0008152	metabolic process
GO:0015914	phospholipid transport
GO:0045332	phospholipid translocation

Cellular Component

GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000143515

View Gene Order

ENSBTAG00000005161

Not yet available

Pathways

NETPATH

REACTOME

REACT_262350

Ion channel transport pathway

REACT_253400

Transmembrane transport of small molecules pathway

REACT_250224

Ion transport by P-type ATPases pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_25149

Ion transport by P-type ATPases pathway

REACT_15518

Transmembrane transport of small molecules pathway

REACT_25300

Ion channel transport pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.30455 Mm.475388

RefSeq

NM_001081182 XM_006501713 XM_006501714 XM_006501715

OMIM

CCDS

CCDS38497

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas