Mus musculus Gene: Acat1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-165951.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Acat1 | ||||||||||||||||||||||
Gene Name | acetyl-Coenzyme A acetyltransferase 1 | ||||||||||||||||||||||
Synonyms | 6330585C21Rik; Acat | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000032047 | ||||||||||||||||||||||
Encoded Proteins |
acetyl-Coenzyme A acetyltransferase 1
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075239:
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 9:53580522-53610382 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | A5.3 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Synthesis of Ketone Bodies pathway
Metabolism of amino acids and derivatives pathway
Ketone body metabolism pathway
Utilization of Ketone Bodies pathway
Branched-chain amino acid catabolism pathway
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KEGG |
Valine, leucine and isoleucine degradation pathway
Lysine degradation pathway
Synthesis and degradation of ketone bodies pathway
Terpenoid backbone biosynthesis pathway
Tryptophan metabolism pathway
Propanoate metabolism pathway
Pyruvate metabolism pathway
Butanoate metabolism pathway
Glyoxylate and dicarboxylate metabolism pathway
Fatty acid degradation pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Synthesis of Ketone Bodies pathway
Utilization of Ketone Bodies pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Branched-chain amino acid catabolism pathway
Metabolism of lipids and lipoproteins pathway
Ketone body metabolism pathway
Metabolism of amino acids and derivatives pathway
Metabolism pathway
Metabolism of amino acids and derivatives pathway
Synthesis of Ketone Bodies pathway
Utilization of Ketone Bodies pathway
Ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Branched-chain amino acid catabolism pathway
Metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
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KEGG |
Terpenoid backbone biosynthesis pathway
Pyruvate metabolism pathway
Valine, leucine and isoleucine degradation pathway
Butanoate metabolism pathway
Propanoate metabolism pathway
Glyoxylate and dicarboxylate metabolism pathway
Tryptophan metabolism pathway
Synthesis and degradation of ketone bodies pathway
Fatty acid degradation pathway
Lysine degradation pathway
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INOH |
Tryptophan degradation pathway
Butanoate metabolism pathway
Citrate cycle pathway
Pyruvate metabolism pathway
Lysine degradation pathway
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PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Mm.293233 Mm.471970 | ||||||||||||||||||||||
RefSeq | NM_144784 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS23184 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||