Version 5.4
Mus musculus Gene: Ggn
Summary
InnateDB Gene IDBG-166224.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ggn
Gene Name gametogenetin
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031493
Encoded Proteins
IDBP-166226
gametogenetin
IDBP-166228
gametogenetin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179168:
This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:29170220-29173933
Strand Forward strand
Band B1
Transcripts
ENSMUST00000098609 ENSMUSP00000096209
ENSMUST00000033886 ENSMUSP00000033886
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006461 protein complex assembly
GO:0007275 multicellular organismal development
GO:0007276 gamete generation
GO:0007283 spermatogenesis
GO:0008104 protein localization
GO:0030154 cell differentiation
Cellular Component
GO:0005635 nuclear envelope
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000179168
View Gene Order
ENSBTAG00000005363
Not yet available
Cross-References
SwissProt
TrEMBL G5E8M4
UniProt Splice Variant
Entrez Gene 243897
UniGene Mm.389886
RefSeq NM_182694 XM_006539944 XM_006539945 XM_006539946 NM_182696
OMIM
CCDS CCDS52168 CCDS21067
HPRD
IMGT
MGI ID MGI:2181461
MGI Symbol Ggn
EMBL AC164564 AF538032 AF538033 AF538034 BC089358 CH466593
GenPept AAH89358 AAP31497 AAP31498 AAP31499 EDL24083
RNA Seq Atlas 243897

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca