InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: S100a13

Summary

InnateDB Gene

IDBG-167784.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

S100a13

Gene Name

S100 calcium binding protein A13

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000042312

Encoded Proteins

IDBP-167786

S100 calcium binding protein A13

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189171:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:90514435-90524581

Strand

Forward strand

Band

Transcripts

ENSMUST00000048138

ENSMUSP00000047737

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005507	copper ion binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0008289	lipid binding
GO:0017134	fibroblast growth factor binding
GO:0042803	protein homodimerization activity
GO:0050786	RAGE receptor binding

Biological Process

GO:0008284	positive regulation of cell proliferation
GO:0008360	regulation of cell shape
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046688	response to copper ion
GO:0050663	cytokine secretion
GO:0050703	interleukin-1 alpha secretion
GO:0051602	response to electrical stimulus

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000189171

View Gene Order

ENSBTAG00000021378

Not yet available

Cross-References

SwissProt

P97352

TrEMBL

Q545H7

UniProt Splice Variant

Entrez Gene

20196

UniGene

RefSeq

NM_009113

OMIM

CCDS

CCDS38504

HPRD

IMGT

MGI ID

MGI:109581

MGI Symbol

S100a13

EMBL

AK002755 AK008895 BC005687 CH466547 X99921

GenPept

AAH05687 BAB22332 BAB25958 CAA68189 EDL15124

RNA Seq Atlas

20196