Version 5.4
Mus musculus Gene: S100a14
Summary
InnateDB Gene IDBG-167833.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100a14
Gene Name S100 calcium binding protein A14
Synonyms 1110013O05Rik; S100a15; S114
Species Mus musculus
Ensembl Gene ENSMUSG00000042306
Encoded Proteins
IDBP-623579
S100 calcium binding protein A14
IDBP-623581
S100 calcium binding protein A14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189334:
This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:90526849-90528837
Strand Forward strand
Band F1
Transcripts
ENSMUST00000167598 ENSMUSP00000126821
ENSMUST00000164481 ENSMUSP00000129862
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0042379 chemokine receptor binding
Biological Process
GO:0006915 apoptotic process
GO:0032496 response to lipopolysaccharide
GO:0034142 toll-like receptor 4 signaling pathway
GO:0042742 defense response to bacterium
GO:0071624 positive regulation of granulocyte chemotaxis
GO:0090026 positive regulation of monocyte chemotaxis
Cellular Component
GO:0005886 plasma membrane
GO:0015630 microtubule cytoskeleton
GO:0030054 cell junction
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000189334
View Gene Order
ENSBTAG00000021377
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9D2Q8
TrEMBL
UniProt Splice Variant
Entrez Gene 66166
UniGene Mm.24006
RefSeq NM_001163525 NM_025393 NM_001163526
OMIM
CCDS CCDS17535 CCDS50971
HPRD
IMGT
MGI ID MGI:1913416
MGI Symbol S100a14
EMBL AK003669 AK019075 BC025607
GenPept AAH25607 BAB22927 BAB31533
RNA Seq Atlas 66166

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca