Mus musculus Gene: Brwd3
Summary
InnateDB Gene IDBG-167844.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brwd3
Gene Name bromodomain and WD repeat domain containing 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000063663
Encoded Proteins
bromodomain and WD repeat domain containing 3
bromodomain and WD repeat domain containing 3
bromodomain and WD repeat domain containing 3
bromodomain and WD repeat domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165288:
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mental retardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:108737016-108834372
Strand Reverse strand
Band D
Transcripts
ENSMUST00000041866 ENSMUSP00000134621
ENSMUST00000101283 ENSMUSP00000098841
ENSMUST00000150434 ENSMUSP00000123588
ENSMUST00000144521 ENSMUSP00000133674
ENSMUST00000134434
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0008360 regulation of cell shape
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt A2AHJ4
TrEMBL G3UXF9
UniProt Splice Variant
Entrez Gene 382236
UniGene Mm.100112 Mm.404226 Mm.404234 Mm.413432 Mm.426127
RefSeq NM_001081477
OMIM
CCDS CCDS41100
HPRD
IMGT
MGI ID MGI:3029414
MGI Symbol Brwd3
EMBL AK050539 AK139563 AK163354 AL731764 BC082562 BX000698
GenPept AAH82562 BAC34314 BAE24064 BAE37315 CAM25065 CAM26827 CAM26828
RNA Seq Atlas 382236