Mus musculus Gene: Arfgap3 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-168036.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Arfgap3 | ||||||||||
Gene Name | ADP-ribosylation factor GTPase activating protein 3 | ||||||||||
Synonyms | 0610009H19Rik; 1810004P07Rik; 1810035F16Rik; 9130416J18Rik; Arfgap1 | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Gene | ENSMUSG00000054277 | ||||||||||
Encoded Proteins |
ADP-ribosylation factor GTPase activating protein 3
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000242247:
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 15:83299740-83350247 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | E1 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME | |||||||||||
KEGG |
Endocytosis pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME | |||||||||||
KEGG |
Endocytosis pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | Q9D8S3 | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 66251 | ||||||||||
UniGene | Mm.258910 Mm.473149 | ||||||||||
RefSeq | NM_025445 XM_006521253 XM_006521254 XM_006521255 XM_006521256 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS49683 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
MGI ID | MGI:1913501 | ||||||||||
MGI Symbol | Arfgap3 | ||||||||||
EMBL | AK007732 AK028990 AK075788 AK169107 BC004081 BC060369 | ||||||||||
GenPept | AAH04081 AAH60369 BAB25220 BAC26229 BAC35959 BAE40889 | ||||||||||
RNA Seq Atlas | 66251 | ||||||||||