Mus musculus Gene: Cpn1 | |||||||||
---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||
InnateDB Gene | IDBG-168895.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Cpn1 | ||||||||
Gene Name | carboxypeptidase N, polypeptide 1 | ||||||||
Synonyms | 0610011F20Rik; CPN | ||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000025196 | ||||||||
Encoded Proteins |
carboxypeptidase N, polypeptide 1
|
||||||||
Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120054:
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008] |
||||||||
Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 19:43956307-43986556 | ||||||||
Strand | Reverse strand | ||||||||
Band | C3 | ||||||||
Transcripts |
|
||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
|
||||||||
Gene Ontology | |||||||||
Molecular Function |
|
||||||||
Biological Process |
|
||||||||
Cellular Component |
|
||||||||
Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||
Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Insulin processing pathway
Metabolism of proteins pathway
Peptide hormone metabolism pathway
|
||||||||
KEGG | |||||||||
INOH | |||||||||
PID NCI | |||||||||
Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Mm.206774 | ||||||||
RefSeq | NM_030703 | ||||||||
OMIM | |||||||||
CCDS | CCDS29840 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | |||||||||
MGI Symbol | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||