Version 5.4
Homo sapiens Gene: MTFMT
Summary
InnateDB Gene IDBG-16959.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTFMT
Gene Name mitochondrial methionyl-tRNA formyltransferase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000103707
Encoded Proteins
IDBP-16961
mitochondrial methionyl-tRNA formyltransferase
IDBP-593945
mitochondrial methionyl-tRNA formyltransferase
IDBP-746321
IDBP-600385
mitochondrial methionyl-tRNA formyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:65001512-65029639
Strand Reverse strand
Band q22.31
Transcripts
ENST00000220058 ENSP00000220058
ENST00000558460 ENSP00000452646
ENST00000560717 ENSP00000457257
ENST00000543678 ENSP00000443754
ENST00000558614
ENST00000561025
ENST00000559633
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004479 methionyl-tRNA formyltransferase activity
GO:0016742 hydroxymethyl-, formyl- and related transferase activity
Biological Process
GO:0006413 translational initiation
GO:0009058 biosynthetic process
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059183
View Gene Order
ENSBTAG00000021630
Not yet available
Pathways
NETPATH
REACTOME
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_267673
Mitochondrial translation pathway
REACT_267680
Mitochondrial translation initiation pathway
KEGG
hsa00670
One carbon pool by folate pathway
hsa00970
Aminoacyl-tRNA biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.531615
RefSeq NM_139242 XM_005254158
HUGO
OMIM
CCDS CCDS45280
HPRD 14799
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca