Homo sapiens Gene: MTFMT
Summary
InnateDB Gene IDBG-16959.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTFMT
Gene Name mitochondrial methionyl-tRNA formyltransferase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000103707
Encoded Proteins
mitochondrial methionyl-tRNA formyltransferase
mitochondrial methionyl-tRNA formyltransferase
mitochondrial methionyl-tRNA formyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:65001512-65029639
Strand Reverse strand
Band q22.31
Transcripts
ENST00000220058 ENSP00000220058
ENST00000558460 ENSP00000452646
ENST00000560717 ENSP00000457257
ENST00000543678 ENSP00000443754
ENST00000558614
ENST00000561025
ENST00000559633
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004479 methionyl-tRNA formyltransferase activity
GO:0016742 hydroxymethyl-, formyl- and related transferase activity
Biological Process
GO:0006413 translational initiation
GO:0009058 biosynthetic process
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
KEGG
One carbon pool by folate pathway
Aminoacyl-tRNA biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q96DP5
TrEMBL H3BTN9
UniProt Splice Variant
Entrez Gene 123263
UniGene Hs.531615
RefSeq NM_139242 XM_005254158
HUGO HGNC:29666
OMIM 611766
CCDS CCDS45280
HPRD 14799
IMGT
EMBL AC013553 AC103691 AK055688 BC016630 BC033687
GenPept AAH16630 AAH33687 BAB70984
RNA Seq Atlas 123263