Version 5.4
Mus musculus Gene: Fbln2
Summary
InnateDB Gene IDBG-170003.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbln2
Gene Name fibulin 2
Synonyms 5730577E14Rik; FIBL-2
Species Mus musculus
Ensembl Gene ENSMUSG00000064080
Encoded Proteins
IDBP-170005
fibulin 2
IDBP-253751
fibulin 2
IDBP-540787
fibulin 2
IDBP-531606
fibulin 2
IDBP-536204
fibulin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163520:
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:91212455-91272540
Strand Forward strand
Band D1
Transcripts
ENSMUST00000041544 ENSMUSP00000048334
ENSMUST00000113498 ENSMUSP00000109126
ENSMUST00000153364 ENSMUSP00000120101
ENSMUST00000132021 ENSMUSP00000116456
ENSMUST00000134974 ENSMUSP00000116302
ENSMUST00000147371
ENSMUST00000134286
ENSMUST00000137029
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0010811 positive regulation of cell-substrate adhesion
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163520
View Gene Order
ENSBTAG00000004014
Not yet available
Pathways
NETPATH
REACTOME
REACT_198996
Elastic fibre formation pathway
REACT_198998
Molecules associated with elastic fibres pathway
REACT_206066
Extracellular matrix organization pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150331
Molecules associated with elastic fibres pathway
REACT_150366
Elastic fibre formation pathway
REACT_118779
Extracellular matrix organization pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.249146 Mm.429387 Mm.452718 Mm.481572
RefSeq NM_001081437 NM_007992 XM_006505530
OMIM
CCDS CCDS39566 CCDS39567
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca