Version 5.4
Mus musculus Gene: Pip5k1a
Summary
InnateDB Gene IDBG-171304.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pip5k1a
Gene Name phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
Synonyms PI4P5K-I[a]; PIP5K1-alpha; PIP5KIalpha; Pipk5a
Species Mus musculus
Ensembl Gene ENSMUSG00000028126
Encoded Proteins
IDBP-171306
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
IDBP-267105
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
IDBP-267109
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
IDBP-267111
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143398:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:95058530-95106930
Strand Reverse strand
Band F2.1
Transcripts
ENSMUST00000005768 ENSMUSP00000005768
ENSMUST00000107236 ENSMUSP00000102855
ENSMUST00000107233 ENSMUSP00000102852
ENSMUST00000107232 ENSMUSP00000102851
ENSMUST00000107231
ENSMUST00000107229
ENSMUST00000151335
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016307 phosphatidylinositol phosphate kinase activity
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0019900 kinase binding
Biological Process
GO:0008654 phospholipid biosynthetic process
GO:0010761 fibroblast migration
GO:0031532 actin cytoskeleton reorganization
GO:0032863 activation of Rac GTPase activity
GO:0046488 phosphatidylinositol metabolic process
GO:0046854 phosphatidylinositol phosphorylation
GO:0048041 focal adhesion assembly
GO:0060326 cell chemotaxis
GO:0072661 protein targeting to plasma membrane
GO:0097178 ruffle assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex
GO:0005886 plasma membrane
GO:0016607 nuclear speck
GO:0030027 lamellipodium
GO:0032587 ruffle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143398
View Gene Order
ENSBTAG00000006099
Not yet available
Pathways
NETPATH
REACTOME
REACT_198973
Synthesis of PIPs at the plasma membrane pathway
REACT_199016
PI Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
mmu04070
Phosphatidylinositol signaling system pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu00562
Inositol phosphate metabolism pathway
mmu04666
Fc gamma R-mediated phagocytosis pathway
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_12
BCR pathway
REACTOME
REACT_121025
Synthesis of PIPs at the plasma membrane pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
hsa04666
Fc gamma R-mediated phagocytosis pathway
hsa04144
Endocytosis pathway
INOH
INOH website
Inositol phosphate metabolism pathway
PID NCI
arf_3pathway
Arf1 pathway
rac1_pathway
RAC1 signaling pathway
arf6downstreampathway
Arf6 downstream pathway
ecadherin_keratinocyte_pathway
E-cadherin signaling in keratinocytes
avb3_opn_pathway
Osteopontin-mediated events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.296409 Mm.402240
RefSeq NM_008847 XM_006501130
OMIM
CCDS CCDS38542
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca