InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Stra6

Summary

InnateDB Gene

IDBG-171524.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Stra6

Gene Name

stimulated by retinoic acid gene 6

Synonyms

AI891933

Species

Mus musculus

Ensembl Gene

ENSMUSG00000032327

Encoded Proteins

IDBP-171526

stimulated by retinoic acid gene 6

IDBP-171528

stimulated by retinoic acid gene 6

IDBP-534445

stimulated by retinoic acid gene 6

IDBP-534697

stimulated by retinoic acid gene 6

IDBP-534978

stimulated by retinoic acid gene 6

IDBP-536300

stimulated by retinoic acid gene 6

IDBP-536534

stimulated by retinoic acid gene 6

IDBP-532182

stimulated by retinoic acid gene 6

IDBP-532038

stimulated by retinoic acid gene 6

IDBP-535641

stimulated by retinoic acid gene 6

IDBP-542738

stimulated by retinoic acid gene 6

IDBP-626519

stimulated by retinoic acid gene 6

IDBP-626520

stimulated by retinoic acid gene 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137868:
The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:58063788-58153996

Strand

Forward strand

Band

Transcripts

ENSMUST00000085677	ENSMUSP00000082820
ENSMUST00000034880	ENSMUSP00000034880
ENSMUST00000145886
ENSMUST00000136154	ENSMUSP00000119062
ENSMUST00000128021	ENSMUSP00000117832
ENSMUST00000133287	ENSMUSP00000114346
ENSMUST00000136338	ENSMUSP00000115314
ENSMUST00000134955	ENSMUSP00000117280
ENSMUST00000147134	ENSMUSP00000115315
ENSMUST00000128378	ENSMUSP00000115511
ENSMUST00000150820	ENSMUSP00000122373
ENSMUST00000134450	ENSMUSP00000118242
ENSMUST00000170397	ENSMUSP00000130232
ENSMUST00000167479	ENSMUSP00000128417

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0051183	vitamin transporter activity

Biological Process

GO:0001568	blood vessel development
GO:0001822	kidney development
GO:0003184	pulmonary valve morphogenesis
GO:0003281	ventricular septum development
GO:0007507	heart development
GO:0007612	learning
GO:0007631	feeding behavior
GO:0030324	lung development
GO:0030325	adrenal gland development
GO:0030540	female genitalia development
GO:0034633	retinol transport
GO:0042297	vocal learning
GO:0042573	retinoic acid metabolic process
GO:0043583	ear development
GO:0043585	nose morphogenesis
GO:0046427	positive regulation of JAK-STAT cascade
GO:0048286	lung alveolus development
GO:0048520	positive regulation of behavior
GO:0048546	digestive tract morphogenesis
GO:0048566	embryonic digestive tract development
GO:0048589	developmental growth
GO:0048745	smooth muscle tissue development
GO:0048844	artery morphogenesis
GO:0050890	cognition
GO:0050905	neuromuscular process
GO:0060322	head development
GO:0060323	head morphogenesis
GO:0060325	face morphogenesis
GO:0060426	lung vasculature development
GO:0060539	diaphragm development
GO:0060900	embryonic camera-type eye formation
GO:0061029	eyelid development in camera-type eye
GO:0061038	uterus morphogenesis
GO:0061143	alveolar primary septum development
GO:0061156	pulmonary artery morphogenesis
GO:0061205	paramesonephric duct development
GO:0071939	vitamin A import
GO:0097070	ductus arteriosus closure