Version 5.4
Mus musculus Gene: Cpt2
Summary
InnateDB Gene IDBG-172182.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cpt2
Gene Name carnitine palmitoyltransferase 2
Synonyms AI323697; CPTII
Species Mus musculus
Ensembl Gene ENSMUSG00000028607
Encoded Proteins
IDBP-172184
carnitine palmitoyltransferase 2
IDBP-268195
carnitine palmitoyltransferase 2
IDBP-268197
carnitine palmitoyltransferase 2
IDBP-534403
carnitine palmitoyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157184:
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:107903981-107923610
Strand Reverse strand
Band C7
Transcripts
ENSMUST00000030345 ENSMUSP00000030345
ENSMUST00000106720 ENSMUSP00000102331
ENSMUST00000106719 ENSMUSP00000102330
ENSMUST00000141738
ENSMUST00000131644 ENSMUSP00000114362
ENSMUST00000175651
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004095 carnitine O-palmitoyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006810 transport
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000157184
View Gene Order
ENSBTAG00000014649
Not yet available
Pathways
NETPATH
REACTOME
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_257219
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_198602
PPARA activates gene expression pathway
REACT_257268
Import of palmitoyl-CoA into the mitochondrial matrix pathway
KEGG
mmu03320
PPAR signaling pathway pathway
mmu00071
Fatty acid degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_116145
PPARA activates gene expression pathway
REACT_19241
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_11082
Import of palmitoyl-CoA into the mitochondrial matrix pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00071
Fatty acid degradation pathway
hsa03320
PPAR signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.307620
RefSeq NM_009949
OMIM
CCDS CCDS18443
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca