Version 5.4
| Mus musculus Gene: Jam2 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-172706.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Jam2 | ||||||
| Gene Name | junction adhesion molecule 2 | ||||||
| Synonyms | 1110002N23Rik; 2410030G21Rik; 2410167M24Rik; JAM-2; JAM-B; Jcam2; VE-JAM | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000053062 | ||||||
| Encoded Proteins |
junction adhesion molecule 2
junction adhesion molecule 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154721:
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 16:84774123-84825928 | ||||||
| Strand | Forward strand | ||||||
| Band | C3.3 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
Hemostasis pathway
Cell surface interactions at the vascular wall pathway
Extracellular matrix organization pathway
Integrin cell surface interactions pathway
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| KEGG |
Tight junction pathway
Cell adhesion molecules (CAMs) pathway
Leukocyte transendothelial migration pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
Cell surface interactions at the vascular wall pathway
Integrin cell surface interactions pathway
Extracellular matrix organization pathway
Hemostasis pathway
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| KEGG |
Cell adhesion molecules (CAMs) pathway
Epithelial cell signaling in Helicobacter pylori infection pathway
Leukocyte transendothelial migration pathway
Tight junction pathway
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| INOH | |||||||
| PID NCI |
Beta1 integrin cell surface interactions
Alpha4 beta1 integrin signaling events
amb2 Integrin signaling
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| Cross-References | |||||||
| SwissProt | Q9JI59 | ||||||
| TrEMBL | Q9CWD9 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 67374 | ||||||
| UniGene | Mm.395117 Mm.397939 Mm.401447 Mm.41758 | ||||||
| RefSeq | NM_023844 XM_006523075 XM_006523076 | ||||||
| OMIM | |||||||
| CCDS | CCDS37381 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1933820 | ||||||
| MGI Symbol | Jam2 | ||||||
| EMBL | AC164162 AF255911 AJ291757 AK010616 AK010826 AK013914 AK028757 AK045095 AK078128 BC028778 CT027693 | ||||||
| GenPept | AAF81224 AAH28778 BAB27064 BAB27208 BAB29053 BAC26102 BAC32219 BAC37139 CAC20699 CAO78081 | ||||||
| RNA Seq Atlas | 67374 | ||||||