Version 5.4
Mus musculus Gene: Atp5j
Summary
InnateDB Gene IDBG-172784.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp5j
Gene Name ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
Synonyms CF6
Species Mus musculus
Ensembl Gene ENSMUSG00000022890
Encoded Proteins
IDBP-172786
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
IDBP-252282
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
IDBP-252284
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
IDBP-539690
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a component of mitochondrial adenosine triphosphate synthase, which catalyzes the conversion of ATP from ADP. Mitochondrial adenosine triphosphate synthase consists of extrinsic and intrinsic membrane domains that are joined by a stalk. The protein encoded by this gene is a subunit of the stalk domain. A bi-directional promoter that drives expression of this gene has been has been identified. Pseudogenes of this gene are found on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:84827866-84835625
Strand Reverse strand
Band C3.3
Transcripts
ENSMUST00000023608 ENSMUSP00000023608
ENSMUST00000114193 ENSMUSP00000109831
ENSMUST00000114191 ENSMUSP00000109829
ENSMUST00000144799
ENSMUST00000146103
ENSMUST00000138279 ENSMUSP00000122527
ENSMUST00000146225
ENSMUST00000127651
ENSMUST00000140036
ENSMUST00000155956
ENSMUST00000150502
ENSMUST00000148787
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015078 hydrogen ion transmembrane transporter activity
GO:0016887 ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0015986 ATP synthesis coupled proton transport
GO:0021762 substantia nigra development
Cellular Component
GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005753 mitochondrial proton-transporting ATP synthase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000154723
View Gene Order
ENSBTAG00000000605
Not yet available
Pathways
NETPATH
REACTOME
REACT_189162
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_188937
Metabolism pathway
REACT_261922
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_245290
Formation of ATP by chemiosmotic coupling pathway
KEGG
mmu00190
Oxidative phosphorylation pathway
mmu05010
Alzheimer's disease pathway
mmu05012
Parkinson's disease pathway
mmu05016
Huntington's disease pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_6759
Formation of ATP by chemiosmotic coupling pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
REACT_212639
Formation of ATP by chemiosmotic coupling pathway
REACT_215469
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_218878
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_219139
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
hnf3apathway
FOXA1 transcription factor network
Cross-References
SwissProt
TrEMBL E9QAD6 Q812D0
UniProt Splice Variant
Entrez Gene 11957
UniGene Mm.487472
RefSeq NM_016755 XM_006522875 XM_006522876 XM_006522877
OMIM
CCDS CCDS28283
HPRD
IMGT
MGI ID MGI:107777
MGI Symbol Atp5j
EMBL AC164162 AF346288
GenPept AAO27831
RNA Seq Atlas 11957

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca