Mus musculus Gene: Bhmt2 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-173016.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Bhmt2 | ||||||||||
Gene Name | betaine-homocysteine methyltransferase 2 | ||||||||||
Synonyms | C81077; D13Ucla2 | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Gene | ENSMUSG00000042118 | ||||||||||
Encoded Proteins |
betaine-homocysteine methyltransferase 2
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132840:
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 13:93655720-93674302 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | C3 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
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Gene ID
Gene Order
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Cross-References | |||||||||||
SwissProt | Q91WS4 | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 64918 | ||||||||||
UniGene | Mm.29981 | ||||||||||
RefSeq | NM_022884 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS26689 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
MGI ID | MGI:1891379 | ||||||||||
MGI Symbol | Bhmt2 | ||||||||||
EMBL | AC158524 AF257474 AK090308 AK145901 BC013515 CT030023 | ||||||||||
GenPept | AAG41357 AAH13515 BAC41163 BAE26737 CAO77969 | ||||||||||
RNA Seq Atlas | 64918 | ||||||||||