Version 5.4
Mus musculus Gene: Dock10
Summary
InnateDB Gene IDBG-173295.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dock10
Gene Name dedicator of cytokinesis 10
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038608
Encoded Proteins
IDBP-173297
dedicator of cytokinesis 10
IDBP-789533
dedicator of cytokinesis 10
IDBP-789534
dedicator of cytokinesis 10
IDBP-789535
dedicator of cytokinesis 10
IDBP-789536
dedicator of cytokinesis 10
IDBP-789539
dedicator of cytokinesis 10
IDBP-789540
dedicator of cytokinesis 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135905:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:80501073-80758527
Strand Reverse strand
Band C5
Transcripts
ENSMUST00000077946 ENSMUSP00000077099
ENSMUST00000190595 ENSMUSP00000139567
ENSMUST00000187774 ENSMUSP00000140085
ENSMUST00000189486 ENSMUSP00000140868
ENSMUST00000190983 ENSMUSP00000140719
ENSMUST00000186835
ENSMUST00000187885
ENSMUST00000191505
ENSMUST00000186087 ENSMUSP00000140102
ENSMUST00000191449 ENSMUSP00000140513
ENSMUST00000187698
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005488 binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0030334 regulation of cell migration
GO:0032319 regulation of Rho GTPase activity
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135905
View Gene Order
ENSBTAG00000000581
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
KEGG
INOH
INOH website
Integrin signaling pathway pathway
PID NCI
cdc42_reg_pathway
Regulation of CDC42 activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001285927 NM_175291 XM_006496470 XM_006496471 XM_006496472 XM_006496473 XM_006496474 XM_006496475 XM_006496476 XM_006496477
OMIM
CCDS CCDS48297
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca