Version 5.4
Mus musculus Gene: Lsm14a
Summary
InnateDB Gene IDBG-173430.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lsm14a
Gene Name LSM14 homolog A (SCD6, S. cerevisiae)
Synonyms 2700023B17Rik; AA407828; AU017544; Tral
Species Mus musculus
Ensembl Gene ENSMUSG00000066568
Encoded Proteins
IDBP-173432
LSM14 homolog A (SCD6, S. cerevisiae)
IDBP-532214
LSM14 homolog A (SCD6, S. cerevisiae)
IDBP-538028
LSM14 homolog A (SCD6, S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000257103:
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:34344646-34389540
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000085585 ENSMUSP00000082723
ENSMUST00000155256 ENSMUSP00000118766
ENSMUST00000133046 ENSMUSP00000119461
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003690 double-stranded DNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006417 regulation of translation
GO:0007275 multicellular organismal development
GO:0033962 cytoplasmic mRNA processing body assembly
GO:0039529 RIG-I signaling pathway
GO:0051607 defense response to virus
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000257103
View Gene Order
ENSBTAG00000000630
Not yet available
Cross-References
SwissProt
TrEMBL A2BH69
UniProt Splice Variant
Entrez Gene 67070
UniGene Mm.276503 Mm.474544
RefSeq XM_006540303 NM_025948
OMIM
CCDS CCDS21140
HPRD
IMGT
MGI ID MGI:1914320
MGI Symbol Lsm14a
EMBL BX537302 BX539342
GenPept
RNA Seq Atlas 67070

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca