Mus musculus Gene: Itgb6 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-173466.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Itgb6 | ||||||||||
Gene Name | integrin beta 6 | ||||||||||
Synonyms | 2210409C20Rik; 4831415H04Rik | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Gene | ENSMUSG00000026971 | ||||||||||
Encoded Proteins |
integrin beta 6
integrin beta 6
integrin beta 6
integrin beta 6
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115221:
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 2:60598292-60722643 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | C1.2 | ||||||||||
Transcripts | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME |
Elastic fibre formation pathway
Molecules associated with elastic fibres pathway
Extracellular matrix organization pathway
Integrin cell surface interactions pathway
ECM proteoglycans pathway
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KEGG |
ECM-receptor interaction pathway
Regulation of actin cytoskeleton pathway
Focal adhesion pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Hypertrophic cardiomyopathy (HCM) pathway
Dilated cardiomyopathy pathway
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INOH |
Integrin signaling pathway pathway
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PID NCI | |||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Integrin cell surface interactions pathway
Molecules associated with elastic fibres pathway
Elastic fibre formation pathway
Extracellular matrix organization pathway
ECM proteoglycans pathway
Extracellular matrix organization pathway
Molecules associated with elastic fibres pathway
Elastic fibre formation pathway
Integrin cell surface interactions pathway
ECM proteoglycans pathway
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KEGG |
Regulation of actin cytoskeleton pathway
ECM-receptor interaction pathway
Focal adhesion pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Hypertrophic cardiomyopathy (HCM) pathway
Dilated cardiomyopathy pathway
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INOH |
Integrin signaling pathway pathway
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PID NCI |
Integrin family cell surface interactions
Beta5 beta6 beta7 and beta8 integrin cell surface interactions
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Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | B1AYG6 B1AYG7 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 16420 | ||||||||||
UniGene | Mm.98193 | ||||||||||
RefSeq | NM_001159564 NM_021359 XM_006498808 XM_006498809 XM_006498810 XM_006498811 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS16060 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
MGI ID | MGI:96615 | ||||||||||
MGI Symbol | Itgb6 | ||||||||||
EMBL | AL928546 AL928833 AL929012 | ||||||||||
GenPept | |||||||||||
RNA Seq Atlas | 16420 | ||||||||||