Version 5.4
Homo sapiens Gene: GBAS
Summary
InnateDB Gene IDBG-17349.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GBAS
Gene Name glioblastoma amplified sequence
Synonyms NIPSNAP2
Species Homo sapiens
Ensembl Gene ENSG00000146729
Encoded Proteins
IDBP-17351
glioblastoma amplified sequence
IDBP-375936
glioblastoma amplified sequence
IDBP-375943
glioblastoma amplified sequence
IDBP-375948
glioblastoma amplified sequence
IDBP-375950
glioblastoma amplified sequence
IDBP-375954
glioblastoma amplified sequence
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. The encoded protein is localized to mitochondria and plays a role in oxidative phosphorylation. A pseudogene of this gene is located on the long arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:55951793-56000181
Strand Forward strand
Band p11.2
Transcripts
ENST00000322090 ENSP00000313050
ENST00000446692 ENSP00000406336
ENST00000446778 ENSP00000406855
ENST00000456204 ENSP00000398498
ENST00000437587 ENSP00000401185
ENST00000415967 ENSP00000409266
ENST00000470036
ENST00000487370
ENST00000472404
ENST00000497279
ENST00000464772
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
Experimentally validated
Total 40 [view]
Protein-Protein 40 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006119 oxidative phosphorylation
GO:0006754 ATP biosynthetic process
GO:2000984 negative regulation of ATP citrate synthase activity
Cellular Component
GO:0005739 mitochondrion
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029432
View Gene Order
ENSBTAG00000031598
Not yet available
Cross-References
SwissProt O75323
TrEMBL
UniProt Splice Variant
Entrez Gene 2631
UniGene Hs.437367 Hs.591069
RefSeq NM_001202469 NM_001483
HUGO HGNC:4179
OMIM 603004
CCDS CCDS56488 CCDS5521
HPRD 04302
IMGT
EMBL AC092579 AF029786 AJ001259 AK097049 BC000732 BC001837 BC030821 BT007112 CH471140 CR407612
GenPept AAC29002 AAH00732 AAH01837 AAH30821 AAP35776 CAA04633 CAG28540 EAX07966 EAX07967
RNA Seq Atlas 2631

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca