Version 5.4
Mus musculus Gene: As3mt
Summary
InnateDB Gene IDBG-173546.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol As3mt
Gene Name arsenic (+3 oxidation state) methyltransferase
Synonyms 2310045H08Rik; Cyt19
Species Mus musculus
Ensembl Gene ENSMUSG00000003559
Encoded Proteins
IDBP-173548
arsenic (+3 oxidation state) methyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000214435:
AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:46707443-46741095
Strand Forward strand
Band C3
Transcripts
ENSMUST00000003655 ENSMUSP00000003655
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0008168 methyltransferase activity
GO:0030791 arsenite methyltransferase activity
GO:0030792 methylarsonite methyltransferase activity
Biological Process
GO:0006464 cellular protein modification process
GO:0008152 metabolic process
GO:0009404 toxin metabolic process
GO:0018872 arsonoacetate metabolic process
GO:0032259 methylation
GO:0046685 response to arsenic-containing substance
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000214435
View Gene Order
ENSBTAG00000036127
Not yet available
Cross-References
SwissProt Q91WU5
TrEMBL
UniProt Splice Variant
Entrez Gene 57344
UniGene Mm.28566
RefSeq NM_020577
OMIM
CCDS CCDS50458
HPRD
IMGT
MGI ID MGI:1929882
MGI Symbol As3mt
EMBL AC161865 AF166383 BC013468 BC145663
GenPept AAF00618 AAI45664
RNA Seq Atlas 57344

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca