Mus musculus Gene: Tbc1d8b
Summary
InnateDB Gene IDBG-174316.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d8b
Gene Name TBC1 domain family, member 8B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000042473
Encoded Proteins
TBC1 domain family, member 8B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133138:
This gene encodes a protein with a TBC (Tre-2/Bub2/CDC16) domain. Some mammalian proteins with this domain have been shown to function as Rab-GAPs by binding to specific Rab proteins and affecting their GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:139684996-139753405
Strand Forward strand
Band F1
Transcripts
ENSMUST00000096313 ENSMUSP00000094036
ENSMUST00000123430
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005097 Rab GTPase activator activity
GO:0005509 calcium ion binding
Biological Process
GO:0008150 biological_process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Membrane Trafficking pathway
Golgi Associated Vesicle Biogenesis pathway
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
trans-Golgi Network Vesicle Budding pathway
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.275869
RefSeq NM_001081499 XM_006528546
OMIM
CCDS CCDS41146
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas