Version 5.4
Mus musculus Gene: Trip12
Summary
InnateDB Gene IDBG-174830.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trip12
Gene Name thyroid hormone receptor interactor 12
Synonyms 1110036I07Rik; 6720416K24Rik; AA410158; Gtl6; TRIP-12
Species Mus musculus
Ensembl Gene ENSMUSG00000026219
Encoded Proteins
IDBP-174832
thyroid hormone receptor interactor 12
IDBP-788234
thyroid hormone receptor interactor 12
IDBP-788235
thyroid hormone receptor interactor 12
IDBP-788237
thyroid hormone receptor interactor 12
IDBP-788238
thyroid hormone receptor interactor 12
IDBP-788239
thyroid hormone receptor interactor 12
IDBP-788240
thyroid hormone receptor interactor 12
IDBP-788242
thyroid hormone receptor interactor 12
IDBP-788243
thyroid hormone receptor interactor 12
IDBP-788244
thyroid hormone receptor interactor 12
IDBP-788245
thyroid hormone receptor interactor 12
IDBP-788246
thyroid hormone receptor interactor 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153827:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:84721189-84840516
Strand Reverse strand
Band C5
Transcripts
ENSMUST00000027421 ENSMUSP00000027421
ENSMUST00000186465 ENSMUSP00000140224
ENSMUST00000189670 ENSMUSP00000140789
ENSMUST00000186648 ENSMUSP00000139563
ENSMUST00000187733 ENSMUSP00000140675
ENSMUST00000191187
ENSMUST00000185720
ENSMUST00000189841 ENSMUSP00000140879
ENSMUST00000190125
ENSMUST00000185909 ENSMUSP00000139986
ENSMUST00000186894 ENSMUSP00000140267
ENSMUST00000185567
ENSMUST00000185672
ENSMUST00000190464 ENSMUSP00000141035
ENSMUST00000190474
ENSMUST00000189496 ENSMUSP00000139682
ENSMUST00000190067 ENSMUSP00000140817
ENSMUST00000187818 ENSMUSP00000140917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046966 thyroid hormone receptor binding
Biological Process
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0009790 embryo development
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1901315 negative regulation of histone H2A K63-linked ubiquitination
GO:2000780 negative regulation of double-strand break repair
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000153827
View Gene Order
ENSBTAG00000021653
Not yet available
Pathways
NETPATH
REACTOME
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_230745
Immune System pathway
REACT_199115
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
mmu04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q3TP48
UniProt Splice Variant
Entrez Gene 14897
UniGene
RefSeq NM_133975 XM_006496409 XM_006496410 XM_006496411 XM_006496412 XM_006496413 XM_006496414 XM_006496415 XM_006496416 XM_006496417 XM_006496421 XM_006496423 XM_006496424 XM_006496425 XM_006496426 XM_006496427 XM_006496428
OMIM
CCDS CCDS35633
HPRD
IMGT
MGI ID MGI:1309481
MGI Symbol Trip12
EMBL AK164719
GenPept BAE37889
RNA Seq Atlas 14897

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca