Version 5.4
Mus musculus Gene: Camk1
Summary
InnateDB Gene IDBG-176348.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Camk1
Gene Name calcium/calmodulin-dependent protein kinase I
Synonyms AI505105; CaMKIalpha; D6Ertd263e
Species Mus musculus
Ensembl Gene ENSMUSG00000030272
Encoded Proteins
IDBP-176350
calcium/calmodulin-dependent protein kinase I
IDBP-536967
calcium/calmodulin-dependent protein kinase I
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134072:
Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq, Jul 2008]
Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:113334124-113343984
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000032409 ENSMUSP00000032409
ENSMUST00000156512
ENSMUST00000153067
ENSMUST00000149497
ENSMUST00000155543 ENSMUSP00000117749
ENSMUST00000156853
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004683 calmodulin-dependent protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0006913 nucleocytoplasmic transport
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0010976 positive regulation of neuron projection development
GO:0032880 regulation of protein localization
GO:0043393 regulation of protein binding
GO:0046827 positive regulation of protein export from nucleus
GO:0051147 regulation of muscle cell differentiation
GO:0051149 positive regulation of muscle cell differentiation
GO:0051835 positive regulation of synapse structural plasticity
GO:0060999 positive regulation of dendritic spine development
GO:0071902 positive regulation of protein serine/threonine kinase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005954 calcium- and calmodulin-dependent protein kinase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134072
View Gene Order
ENSBTAG00000007780
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.277373
RefSeq NM_133926
OMIM
CCDS CCDS20415
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca