Version 5.4
Mus musculus Gene: Apom
Summary
InnateDB Gene IDBG-176786.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Apom
Gene Name apolipoprotein M
Synonyms 1190010O19Rik; G3a; NG20
Species Mus musculus
Ensembl Gene ENSMUSG00000024391
Encoded Proteins
IDBP-176788
apolipoprotein M
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204444:
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35128997-35132050
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000025249 ENSMUSP00000025249
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005319 lipid transporter activity
GO:0005543 phospholipid binding
GO:0016209 antioxidant activity
Biological Process
GO:0009749 response to glucose
GO:0033344 cholesterol efflux
GO:0034375 high-density lipoprotein particle remodeling
GO:0034380 high-density lipoprotein particle assembly
GO:0034384 high-density lipoprotein particle clearance
GO:0034445 negative regulation of plasma lipoprotein particle oxidation
GO:0042157 lipoprotein metabolic process
GO:0043691 reverse cholesterol transport
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0034361 very-low-density lipoprotein particle
GO:0034362 low-density lipoprotein particle
GO:0034364 high-density lipoprotein particle
GO:0034365 discoidal high-density lipoprotein particle
GO:0034366 spherical high-density lipoprotein particle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000204444
View Gene Order
ENSBTAG00000008833
Not yet available
Cross-References
SwissProt Q9Z1R3
TrEMBL
UniProt Splice Variant
Entrez Gene 55938
UniGene
RefSeq NM_018816
OMIM
CCDS CCDS28687
HPRD
IMGT
MGI ID MGI:1930124
MGI Symbol Apom
EMBL AF109719 AF207820 AK004530
GenPept AAC82478 AAF23407 BAB23349
RNA Seq Atlas 55938

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca