Version 5.4
Homo sapiens Gene: DENND4A
Summary
InnateDB Gene IDBG-17699.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DENND4A
Gene Name DENN/MADD domain containing 4A
Synonyms IRLB; MYCPBP
Species Homo sapiens
Ensembl Gene ENSG00000174485
Encoded Proteins
IDBP-375580
DENN/MADD domain containing 4A
IDBP-375585
DENN/MADD domain containing 4A
IDBP-744760
IDBP-745435
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:65658046-65792293
Strand Reverse strand
Band q22.31
Transcripts
ENST00000443035 ENSP00000391167
ENST00000431932 ENSP00000396830
ENST00000564674 ENSP00000457358
ENST00000561863 ENSP00000456605
ENST00000562028
ENST00000562540
ENST00000568515
ENST00000567323
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0017112 Rab guanyl-nucleotide exchange factor activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000053641
View Gene Order
ENSBTAG00000017095
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.513817 Hs.617488 Hs.654567
RefSeq NM_001144823 NM_005848 XM_005254119 XM_005254120 XM_005254121 XM_005254122 XM_006720371 XM_006720372
HUGO
OMIM
CCDS CCDS45285 CCDS53949
HPRD 02662
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca