Version 5.4
| Mus musculus Gene: Klk4 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-177682.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Klk4 | ||||||||
| Gene Name | kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) | ||||||||
| Synonyms | ESMP1; KLK-L1; Prss17; PSTS | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000006948 | ||||||||
| Encoded Proteins |
kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167749:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:43881172-43885804 | ||||||||
| Strand | Forward strand | ||||||||
| Band | B3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | Q9Z0M1 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 56640 | ||||||||
| UniGene | Mm.42080 | ||||||||
| RefSeq | NM_019928 XM_006541014 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS21186 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1861379 | ||||||||
| MGI Symbol | Klk4 | ||||||||
| EMBL | AC134858 AF019979 BC100716 BC100717 BC100718 BC100719 CH466603 | ||||||||
| GenPept | AAC98894 AAI00717 AAI00718 AAI00719 AAI00720 EDL22687 | ||||||||
| RNA Seq Atlas | 56640 | ||||||||