Mus musculus Gene: Adamts3 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-177974.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Adamts3 | ||||||||||||
Gene Name | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3 | ||||||||||||
Synonyms | |||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000043635 | ||||||||||||
Encoded Proteins |
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156140:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 5:89673841-89883334 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | E1 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Collagen biosynthesis and modifying enzymes pathway
Post-translational protein modification pathway
Extracellular matrix organization pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
Collagen formation pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | E9Q287 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 330119 | ||||||||||||
UniGene | Mm.133062 | ||||||||||||
RefSeq | NM_177872 XM_006535013 NM_001081401 XM_006535014 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS51542 CCDS39140 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | MGI:3045353 | ||||||||||||
MGI Symbol | Adamts3 | ||||||||||||
EMBL | AC102039 AC102056 AC156611 | ||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | 330119 | ||||||||||||