Version 5.4
Mus musculus Gene: Alb
Summary
InnateDB Gene IDBG-178482.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Alb
Gene Name albumin
Synonyms Alb-1; Alb1
Species Mus musculus
Ensembl Gene ENSMUSG00000029368
Encoded Proteins
IDBP-178484
albumin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163631:
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:90460889-90476603
Strand Forward strand
Band E1
Transcripts
ENSMUST00000031314 ENSMUSP00000031314
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 137 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 23 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 137 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005504 fatty acid binding
GO:0005515 protein binding
GO:0008144 drug binding
GO:0008270 zinc ion binding
GO:0015643 toxic substance binding
GO:0019825 oxygen binding
GO:0019899 enzyme binding
GO:0030170 pyridoxal phosphate binding
GO:0051087 chaperone binding
Biological Process
GO:0001895 retina homeostasis
GO:0006810 transport
GO:0007584 response to nutrient
GO:0009267 cellular response to starvation
GO:0010033 response to organic substance
GO:0019836 hemolysis by symbiont of host erythrocytes
GO:0043066 negative regulation of apoptotic process
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046689 response to mercury ion
GO:0051659 maintenance of mitochondrion location
GO:0070541 response to platinum ion
Cellular Component
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163631
View Gene Order
ENSBTAG00000017121
Not yet available
Pathways
NETPATH
REACTOME
REACT_230203
Platelet degranulation pathway
REACT_224553
Hemostasis pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_232951
Transport of vitamins, nucleosides, and related molecules pathway
REACT_239346
Recycling of bile acids and salts pathway
REACT_213857
HDL-mediated lipid transport pathway
REACT_188937
Metabolism pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_196575
Scavenging of heme from plasma pathway
REACT_196573
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_238381
Lipid digestion, mobilization, and transport pathway
REACT_211709
Lipoprotein metabolism pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_210189
Transport of organic anions pathway
REACT_206166
Response to elevated platelet cytosolic Ca2+ pathway
REACT_229469
Bile acid and bile salt metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_160163
Scavenging of heme from plasma pathway
REACT_318
Platelet degranulation pathway
REACT_1280
Response to elevated platelet cytosolic Ca2+ pathway
REACT_23988
Transport of organic anions pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_11042
Recycling of bile acids and salts pathway
REACT_13621
HDL-mediated lipid transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_11040
Bile acid and bile salt metabolism pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_160300
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_6823
Lipoprotein metabolism pathway
REACT_111217
Metabolism pathway
REACT_602
Lipid digestion, mobilization, and transport pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_604
Hemostasis pathway
REACT_202252
Platelet degranulation pathway
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_216574
Transport of organic anions pathway
REACT_212432
Lipoprotein metabolism pathway
REACT_223874
Recycling of bile acids and salts pathway
REACT_212196
Hemostasis pathway
REACT_209572
Platelet activation, signaling and aggregation pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_212308
Response to elevated platelet cytosolic Ca2+ pathway
REACT_222480
HDL-mediated lipid transport pathway
REACT_218813
Transport of vitamins, nucleosides, and related molecules pathway
REACT_213817
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_223789
Bile acid and bile salt metabolism pathway
REACT_219139
Metabolism pathway
REACT_219679
Scavenging of heme from plasma pathway
REACT_213267
Lipid digestion, mobilization, and transport pathway
KEGG
INOH
PID NCI
hnf3bpathway
FOXA2 and FOXA3 transcription factor networks
Cross-References
SwissProt P07724
TrEMBL K7R066 Q546G4
UniProt Splice Variant
Entrez Gene 11657
UniGene Mm.16773 Mm.422183
RefSeq NM_009654
OMIM
CCDS CCDS19412
HPRD
IMGT
MGI ID MGI:87991
MGI Symbol Alb
EMBL AJ011413 AJ277794 AJ457860 AK010025 AK050248 AK050644 AK131891 AK160487 BC024643 BC049971 CH466617 JX564908 JX564909 JX564910 M16111 X13060
GenPept AAA37190 AAH24643 AAH49971 AFV73331 AFV73332 AFV73333 BAB26650 BAC34145 BAC34360 BAE20854 BAE35818 CAA09617 CAA31458 CAC81903 CAD29888 EDL05322
RNA Seq Atlas 11657

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca