Mus musculus Gene: Dhx16
Summary
InnateDB Gene IDBG-179309.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dhx16
Gene Name DEAH (Asp-Glu-Ala-His) box polypeptide 16
Synonyms 2410006N22Rik; DBP2; Ddx16; mKIAA0577;
Species Mus musculus
Ensembl Gene ENSMUSG00000024422
Encoded Proteins
DEAH (Asp-Glu-Ala-His) box polypeptide 16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204560:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35879819-35892670
Strand Forward strand
Band B1
Transcripts
ENSMUST00000025292 ENSMUSP00000025292
ENSMUST00000174366 ENSMUSP00000133888
ENSMUST00000172730
ENSMUST00000174449
ENSMUST00000174330
ENSMUST00000173596
ENSMUST00000173967 ENSMUSP00000133818
ENSMUST00000174308
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL Q05BH3
UniProt Splice Variant
Entrez Gene 69192
UniGene Mm.390986
RefSeq NM_026987 XM_006524874 XM_006524873
OMIM
CCDS CCDS28710
HPRD
IMGT
MGI ID MGI:1916442
MGI Symbol Dhx16
EMBL BC046781 CR974451
GenPept AAH46781
RNA Seq Atlas 69192