InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Kcnc3

Summary

InnateDB Gene

IDBG-179357.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kcnc3

Gene Name

potassium voltage gated channel, Shaw-related subfamily, member 3

Synonyms

Kcr2-3; KShIIID; Kv3.3

Species

Mus musculus

Ensembl Gene

ENSMUSG00000062785

Encoded Proteins

IDBP-179359

potassium voltage gated channel, Shaw-related subfamily, member 3

IDBP-265683

potassium voltage gated channel, Shaw-related subfamily, member 3

IDBP-265685

potassium voltage gated channel, Shaw-related subfamily, member 3

IDBP-265687

potassium voltage gated channel, Shaw-related subfamily, member 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131398:
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. [provided by RefSeq, Jul 2008]
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Alternate splicing results in several transcript variants. [provided by RefSeq, Mar 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:44590664-44604754

Strand

Forward strand

Band

Transcripts

ENSMUST00000071062	ENSMUSP00000069754
ENSMUST00000107907	ENSMUSP00000103540
ENSMUST00000107906	ENSMUSP00000103539
ENSMUST00000107905	ENSMUSP00000103538

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005251	delayed rectifier potassium channel activity
GO:0005515	protein binding

Biological Process

GO:0006811	ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0046928	regulation of neurotransmitter secretion
GO:0051260	protein homooligomerization
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane
GO:0030673	axolemma
GO:0031594	neuromuscular junction
GO:0032590	dendrite membrane
GO:0032809	neuronal cell body membrane
GO:0043679	axon terminus

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000131398

View Gene Order

ENSBTAG00000039935

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_75770

Voltage gated Potassium channels pathway

REACT_13685

Neuronal System pathway

REACT_75908

Potassium Channels pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.40312

RefSeq

NM_008422 XM_006540655 XM_006540660

OMIM

CCDS

CCDS39942

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas