Version 5.4
Mus musculus Gene: Kif2a
Summary
InnateDB Gene IDBG-181060.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kif2a
Gene Name kinesin family member 2A
Synonyms C530030B14Rik; Kif2; Kns2; M-kinesin
Species Mus musculus
Ensembl Gene ENSMUSG00000021693
Encoded Proteins
IDBP-181064
kinesin family member 2A
IDBP-400650
kinesin family member 2A
IDBP-400651
kinesin family member 2A
IDBP-400649
kinesin family member 2A
IDBP-541296
kinesin family member 2A
IDBP-540133
kinesin family member 2A
IDBP-541985
kinesin family member 2A
IDBP-542422
kinesin family member 2A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000068796:
The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:106958996-107022126
Strand Reverse strand
Band D2.1
Transcripts
ENSMUST00000022204 ENSMUSP00000022204
ENSMUST00000122233 ENSMUSP00000112715
ENSMUST00000117423 ENSMUSP00000113921
ENSMUST00000117539 ENSMUSP00000113361
ENSMUST00000159772 ENSMUSP00000125644
ENSMUST00000162845 ENSMUSP00000124517
ENSMUST00000125038 ENSMUSP00000125591
ENSMUST00000146395 ENSMUSP00000116070
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement
GO:0007052 mitotic spindle organization
GO:0007067 mitotic nuclear division
GO:0007399 nervous system development
GO:0008152 metabolic process
GO:0030154 cell differentiation
Cellular Component
GO:0000922 spindle pole
GO:0005764 lysosome
GO:0005813 centrosome
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0005876 spindle microtubule
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000068796
View Gene Order
ENSBTAG00000015022
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_224553
Hemostasis pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_188804
Cell Cycle pathway
REACT_230745
Immune System pathway
REACT_241408
M Phase pathway
REACT_199117
Kinesins pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_229531
Adaptive Immune System pathway
REACT_202512
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_121399
MHC class II antigen presentation pathway
REACT_25201
Kinesins pathway
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_115566
Cell Cycle pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_604
Hemostasis pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
plk1_pathway
PLK1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.355686 Mm.450917 Mm.471008
RefSeq NM_001145779 NM_008442 XM_006517535
OMIM
CCDS CCDS26759 CCDS49356
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca