Version 5.4
Mus musculus Gene: Syt6
Summary
InnateDB Gene IDBG-181512.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Syt6
Gene Name synaptotagmin VI
Synonyms 3110037A08Rik; AW048930; sytVI
Species Mus musculus
Ensembl Gene ENSMUSG00000027849
Encoded Proteins
IDBP-181516
synaptotagmin VI
IDBP-400694
synaptotagmin VI
IDBP-400693
synaptotagmin VI
IDBP-400692
synaptotagmin VI
IDBP-400695
synaptotagmin VI
IDBP-541045
synaptotagmin VI
IDBP-531857
synaptotagmin VI
IDBP-536302
synaptotagmin VI
IDBP-787832
synaptotagmin VI
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134207:
The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:103575231-103645569
Strand Forward strand
Band F2.2
Transcripts
ENSMUST00000090697 ENSMUSP00000088196
ENSMUST00000121834 ENSMUSP00000112997
ENSMUST00000118563 ENSMUSP00000113287
ENSMUST00000117221 ENSMUSP00000113373
ENSMUST00000118117 ENSMUSP00000112486
ENSMUST00000132325 ENSMUSP00000116324
ENSMUST00000136049 ENSMUSP00000118124
ENSMUST00000151985 ENSMUSP00000119688
ENSMUST00000183637 ENSMUSP00000138874
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0019905 syntaxin binding
GO:0030276 clathrin binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0007340 acrosome reaction
GO:0060478 acrosomal vesicle exocytosis
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016021 integral component of membrane
GO:0019898 extrinsic component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0097038 perinuclear endoplasmic reticulum
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134207
View Gene Order
ENSBTAG00000018881
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.488213 Mm.88818
RefSeq NM_001276676 NM_001276677 NM_001276679 NM_001276680 NM_001276681 NM_018800 XM_006501704 XM_006501705 XM_006501706 XM_006501707 XM_006501708
OMIM
CCDS CCDS38575 CCDS71296 CCDS71297
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca