Homo sapiens Gene: CLEC2B
Summary
InnateDB Gene IDBG-18177.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC2B
Gene Name C-type lectin domain family 2, member B
Synonyms AICL; CLECSF2; HP10085; IFNRG1;
Species Homo sapiens
Ensembl Gene ENSG00000110852
Encoded Proteins
C-type lectin domain family 2, member B
C-type lectin domain family 2, member B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:9852984-9870136
Strand Reverse strand
Band p13.31
Transcripts
ENST00000228438 ENSP00000228438
ENST00000538152 ENSP00000437946
ENST00000540743
ENST00000539028
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
GO:0005887 integral component of plasma membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL F5H631
UniProt Splice Variant
Entrez Gene 9976
UniGene
RefSeq NM_005127
HUGO HGNC:2053
OMIM 603242
CCDS CCDS8605
HPRD 09129
IMGT
EMBL AC007068 AC091814
GenPept
RNA Seq Atlas 9976