Version 5.4
Mus musculus Gene: Aqp9
Summary
InnateDB Gene IDBG-182767.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aqp9
Gene Name aquaporin 9
Synonyms 1700020I22Rik; AI266899; AQP-9
Species Mus musculus
Ensembl Gene ENSMUSG00000032204
Encoded Proteins
IDBP-182769
aquaporin 9
IDBP-182771
aquaporin 9
IDBP-253599
aquaporin 9
IDBP-537282
aquaporin 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the aquaglyceroporin subfamily of aquaporins. This protein transports water, glycerol, urea, purines and pyrimidines and plays a role in glycerol metabolism and osteoclast differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:71110659-71168682
Strand Reverse strand
Band D
Transcripts
ENSMUST00000074465 ENSMUSP00000074063
ENSMUST00000060917 ENSMUSP00000050127
ENSMUST00000113570 ENSMUSP00000109200
ENSMUST00000144618 ENSMUSP00000116785
ENSMUST00000135892
ENSMUST00000139495
ENSMUST00000153050
ENSMUST00000133239
ENSMUST00000136798
ENSMUST00000138364
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005345 purine nucleobase transmembrane transporter activity
GO:0005350 pyrimidine nucleobase transmembrane transporter activity
GO:0015250 water channel activity
GO:0015254 glycerol channel activity
Biological Process
GO:0006810 transport
GO:0006833 water transport
GO:0006863 purine nucleobase transport
GO:0010033 response to organic substance
GO:0015722 canalicular bile acid transport
GO:0015791 polyol transport
GO:0015793 glycerol transport
GO:0015837 amine transport
GO:0015855 pyrimidine nucleobase transport
GO:0046689 response to mercury ion
GO:0071320 cellular response to cAMP
GO:0072531 pyrimidine-containing compound transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000103569
View Gene Order
ENSBTAG00000013452
Not yet available
Pathways
NETPATH
REACTOME
REACT_198170
Transport of glycerol from adipocytes to the liver by Aquaporins pathway
REACT_226335
Aquaporin-mediated transport pathway
REACT_259079
Passive transport by Aquaporins pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
mmu04976
Bile secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23809
Transport of glycerol from adipocytes to the liver by Aquaporins pathway
REACT_23826
Passive transport by Aquaporins pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_23887
Aquaporin-mediated transport pathway
KEGG
hsa04976
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.449427 Mm.450956 Mm.474342 Mm.485117
RefSeq NM_001271843 NM_022026 XM_006511329 XM_006511330 XM_006511331 XM_006511332 XM_006511333
OMIM
CCDS CCDS23325 CCDS72270
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca