Version 5.4
Mus musculus Gene: Polr2m
Summary
InnateDB Gene IDBG-182931.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Polr2m
Gene Name polymerase (RNA) II (DNA directed) polypeptide M
Synonyms AA407243; AA408799; AI303746; AW553238; D9Wsu138e; Grinl1a; mKIAA4185
Species Mus musculus
Ensembl Gene ENSMUSG00000032199
Encoded Proteins
IDBP-182933
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
IDBP-623415
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
IDBP-623417
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000255529:
This gene encodes a subunit of RNA polymerase II, a protein complex that is responsible for synthesizing messenger RNA in eukaryotes. The encoded protein functions as a component of a specific form of RNA polymerase II termed Pol II(G). This protein may act as a negative regulator of activator-dependent transcription. Alternate splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein). [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:71478437-71485935
Strand Reverse strand
Band D
Transcripts
ENSMUST00000034720 ENSMUSP00000034720
ENSMUST00000163972 ENSMUSP00000132335
ENSMUST00000169804 ENSMUSP00000126403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003899 DNA-directed RNA polymerase activity
Biological Process
GO:0032774 RNA biosynthetic process
GO:0051685 maintenance of ER location
Cellular Component
GO:0005635 nuclear envelope
GO:0016591 DNA-directed RNA polymerase II, holoenzyme
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000255529
View Gene Order
ENSBTAG00000040384
Not yet available
Cross-References
SwissProt
TrEMBL E9PZ03
UniProt Splice Variant
Entrez Gene 28015
UniGene Mm.21094 Mm.403070
RefSeq NM_001164793 NM_178602
OMIM
CCDS CCDS23326 CCDS52853
HPRD
IMGT
MGI ID MGI:107282
MGI Symbol Polr2m
EMBL AC160560
GenPept
RNA Seq Atlas 28015

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca