Version 5.4
| Mus musculus Gene: Rad52 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-182943.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Rad52 | ||||||||
| Gene Name | RAD52 homolog (S. cerevisiae) | ||||||||
| Synonyms | Rad52yh | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000030166 | ||||||||
| Encoded Proteins |
RAD52 homolog (S. cerevisiae)
RAD52 homolog (S. cerevisiae)
RAD52 homolog (S. cerevisiae)
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000002016:
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq, Jul 2008] The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 6:119902698-119922828 | ||||||||
| Strand | Forward strand | ||||||||
| Band | F1 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Assembly of the RAD51-ssDNA nucleoprotein complex pathway
Double-Strand Break Repair pathway
Homologous DNA pairing and strand exchange pathway
Presynaptic phase of homologous DNA pairing and strand exchange pathway
DNA Repair pathway
Homologous Recombination Repair pathway
Homologous recombination repair of replication-independent double-strand breaks pathway
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| KEGG |
Homologous recombination pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Assembly of the RAD51-ssDNA nucleoprotein complex pathway
Presynaptic phase of homologous DNA pairing and strand exchange pathway
Homologous DNA pairing and strand exchange pathway
Homologous Recombination Repair pathway
Double-Strand Break Repair pathway
Homologous recombination repair of replication-independent double-strand breaks pathway
DNA Repair pathway
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| KEGG |
Homologous recombination pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | |||||||||
| RefSeq | NM_001166381 NM_001166382 NM_001166383 NM_011236 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS20477 CCDS51887 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | |||||||||
| MGI Symbol | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||