InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Dis3

Summary

InnateDB Gene

IDBG-183878.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dis3

Gene Name

DIS3 mitotic control homolog (S. cerevisiae)

Synonyms

2810028N01Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000033166

Encoded Proteins

IDBP-183882

DIS3 mitotic control homolog (S. cerevisiae)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083520:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:99076634-99099770

Strand

Reverse strand

Band

E2.2

Transcripts

ENSMUST00000042471

ENSMUSP00000041906

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000175	3'-5'-exoribonuclease activity
GO:0003723	RNA binding
GO:0004519	endonuclease activity
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005515	protein binding

Biological Process

GO:0006364	rRNA processing
GO:0016075	rRNA catabolic process
GO:0043087	regulation of GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0071034	CUT catabolic process
GO:0090305	nucleic acid phosphodiester bond hydrolysis
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic