InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp5f1

Summary

InnateDB Gene

IDBG-183928.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp5f1

Gene Name

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1

Synonyms

C76477

Species

Mus musculus

Ensembl Gene

ENSMUSG00000000563

Encoded Proteins

IDBP-400619

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1

IDBP-532950

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116459:
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the b subunit of the proton channel. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:105942698-105960099

Strand

Reverse strand

Band

F2.2

Transcripts

ENSMUST00000118209	ENSMUSP00000113022
ENSMUST00000133320	ENSMUSP00000115496
ENSMUST00000153666
ENSMUST00000143022
ENSMUST00000123959

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0016887	ATPase activity
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism

Biological Process

GO:0006200	ATP catabolic process
GO:0015986	ATP synthesis coupled proton transport
GO:0021762	substantia nigra development

Cellular Component

GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005753	mitochondrial proton-transporting ATP synthase complex
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome