Mus musculus Gene: Cnot1
Summary
InnateDB Gene IDBG-184242.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cnot1
Gene Name CCR4-NOT transcription complex, subunit 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036550
Encoded Proteins
CCR4-NOT transcription complex, subunit 1
CCR4-NOT transcription complex, subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125107:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:95719451-95807462
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000068452 ENSMUSP00000063565
ENSMUST00000098473 ENSMUSP00000096073
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005488 binding
GO:0005515 protein binding
GO:0030331 estrogen receptor binding
GO:0042974 retinoic acid receptor binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001829 trophectodermal cell differentiation
GO:0006351 transcription, DNA-templated
GO:0006417 regulation of translation
GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly
GO:0031047 gene silencing by RNA
GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:2000036 regulation of stem cell maintenance
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005778 peroxisomal membrane
GO:0016020 membrane
GO:0030014 CCR4-NOT complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Deadenylation of mRNA pathway
Gene Expression pathway
Deadenylation-dependent mRNA decay pathway
KEGG
RNA degradation pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Deadenylation-dependent mRNA decay pathway
Deadenylation of mRNA pathway
Gene Expression pathway
KEGG
RNA degradation pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q6ZQ08
TrEMBL B7ZWL1
UniProt Splice Variant
Entrez Gene 620499
UniGene Mm.259220 Mm.415682
RefSeq NM_001205226 NM_153164 NM_178078 XM_006519750 XM_006530870 XM_006530871 XM_006530872 XM_006530873 XM_006530874 XM_006530875 XM_006543124
OMIM
CCDS CCDS57635
HPRD
IMGT
MGI ID MGI:2442402
MGI Symbol Cnot1
EMBL AC113951 AC127300 AK031357 AK034776 AK048177 AK129258 AK143651 BC018281 BC158073 BC172105
GenPept AAH18281 AAI58074 AAI72105 BAC27364 BAC28830 BAC33267 BAC98068 BAE25479
RNA Seq Atlas 234594 620499