Version 5.4
Mus musculus Gene: Calcrl
Summary
InnateDB Gene IDBG-184603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Calcrl
Gene Name calcitonin receptor-like
Synonyms AV071593; CRLR
Species Mus musculus
Ensembl Gene ENSMUSG00000059588
Encoded Proteins
IDBP-184605
calcitonin receptor-like
IDBP-184607
calcitonin receptor-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064989:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:84330626-84425411
Strand Reverse strand
Band D
Transcripts
ENSMUST00000099944 ENSMUSP00000097527
ENSMUST00000074262 ENSMUSP00000073875
ENSMUST00000151295
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001605 adrenomedullin receptor activity
GO:0001635 calcitonin gene-related polypeptide receptor activity
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004948 calcitonin receptor activity
GO:0005515 protein binding
GO:0008565 protein transporter activity
Biological Process
GO:0001525 angiogenesis
GO:0006171 cAMP biosynthetic process
GO:0006816 calcium ion transport
GO:0006937 regulation of muscle contraction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007507 heart development
GO:0008284 positive regulation of cell proliferation
GO:0015031 protein transport
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0031623 receptor internalization
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050728 negative regulation of inflammatory response
GO:0071329 cellular response to sucrose stimulus
Cellular Component
GO:0005764 lysosome
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000064989
View Gene Order
ENSBTAG00000008483
Not yet available
Pathways
NETPATH
REACTOME
REACT_242871
G alpha (s) signalling events pathway
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_250061
Class B/2 (Secretin family receptors) pathway
REACT_255862
Calcitonin-like ligand receptors pathway
REACT_231468
GPCR ligand binding pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04080
Neuroactive ligand-receptor interaction pathway
mmu04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19327
G alpha (s) signalling events pathway
REACT_18290
Calcitonin-like ligand receptors pathway
REACT_18372
Class B/2 (Secretin family receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
hsa04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.75467
RefSeq NM_018782 XM_006499918
OMIM
CCDS CCDS16184
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca