Version 5.4
Mus musculus Gene: Arpp19
Summary
InnateDB Gene IDBG-184720.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arpp19
Gene Name cAMP-regulated phosphoprotein 19
Synonyms 19kDa; 2700024H10Rik; ARPP-19; Arpp12; AW559096
Species Mus musculus
Ensembl Gene ENSMUSG00000007656
Encoded Proteins
IDBP-184722
cAMP-regulated phosphoprotein 19
IDBP-624122
cAMP-regulated phosphoprotein 19
IDBP-624123
cAMP-regulated phosphoprotein 19
IDBP-624126
cAMP-regulated phosphoprotein 19
IDBP-624131
cAMP-regulated phosphoprotein 19
IDBP-624132
cAMP-regulated phosphoprotein 19
IDBP-624133
cAMP-regulated phosphoprotein 19
IDBP-624135
cAMP-regulated phosphoprotein 19
IDBP-624136
cAMP-regulated phosphoprotein 19
IDBP-624137
cAMP-regulated phosphoprotein 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128989:
The 19-kD cAMP-regulated phosphoprotein plays a role in regulating mitosis by inhibiting protein phosphatase-2A (PP2A; see MIM 176915) (summary by Gharbi-Ayachi et al., 2010 [PubMed 21164014]).[supplied by OMIM, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:75037614-75060313
Strand Forward strand
Band D
Transcripts
ENSMUST00000007800 ENSMUSP00000007800
ENSMUST00000168166 ENSMUSP00000126618
ENSMUST00000169448
ENSMUST00000170308 ENSMUSP00000132350
ENSMUST00000164467 ENSMUSP00000130730
ENSMUST00000168301 ENSMUSP00000132802
ENSMUST00000167885 ENSMUSP00000131597
ENSMUST00000169188 ENSMUSP00000131922
ENSMUST00000170310 ENSMUSP00000125825
ENSMUST00000166549 ENSMUSP00000131987
ENSMUST00000169492 ENSMUSP00000128921
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
GO:0005102 receptor binding
GO:0008601 protein phosphatase type 2A regulator activity
GO:0015459 potassium channel regulator activity
GO:0019212 phosphatase inhibitor activity
GO:0051721 protein phosphatase 2A binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0007067 mitotic nuclear division
GO:0007212 dopamine receptor signaling pathway
GO:0043086 negative regulation of catalytic activity
GO:0045722 positive regulation of gluconeogenesis
GO:0046579 positive regulation of Ras protein signal transduction
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128989
View Gene Order
ENSBTAG00000011022
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_196577
MASTL Facilitates Mitotic Progression pathway
REACT_250557
Mitotic Prophase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150182
MASTL Facilitates Mitotic Progression pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_203310
MASTL Facilitates Mitotic Progression pathway
REACT_216366
M Phase pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_214934
Cell Cycle pathway
REACT_211448
Mitotic Prophase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PXD7 E9Q827
UniProt Splice Variant
Entrez Gene 59046
UniGene Mm.247837 Mm.416753 Mm.456515 Mm.473473
RefSeq NM_001142655 XM_006511327 NM_021548
OMIM
CCDS CCDS52859 CCDS23340
HPRD
IMGT
MGI ID MGI:1891691
MGI Symbol Arpp19
EMBL AJ005983 AK049760 BC040206 CT033761
GenPept AAH40206 BAC33908 CAA06797
RNA Seq Atlas 59046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca