Version 5.4
| Mus musculus Gene: Piga | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-184835.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Piga | ||||||||
| Gene Name | phosphatidylinositol glycan anchor biosynthesis, class A | ||||||||
| Synonyms | AI194334; Pig-a | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000031381 | ||||||||
| Encoded Proteins |
phosphatidylinositol glycan anchor biosynthesis, class A
phosphatidylinositol glycan anchor biosynthesis, class A
phosphatidylinositol glycan anchor biosynthesis, class A
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165195:
This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12. [provided by RefSeq, Jun 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome X:164419793-164433916 | ||||||||
| Strand | Forward strand | ||||||||
| Band | F5 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
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| KEGG |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of glycosylphosphatidylinositol (GPI) pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
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| KEGG |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q64323 | ||||||||
| TrEMBL | A2AIH4 A2AIH5 M0QWH5 M0QWY7 Q3TB52 Q6PDD9 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 18700 | ||||||||
| UniGene | Mm.3781 Mm.401070 Mm.455530 | ||||||||
| RefSeq | NM_011081 XM_006528758 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS30522 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:99461 | ||||||||
| MGI Symbol | Piga | ||||||||
| EMBL | AK032283 AK171453 AL732475 BC058767 BC138755 BC138758 CH466571 D26047 D31863 S78188 | ||||||||
| GenPept | AAH58767 AAI38756 AAI38759 AAP32009 BAA05047 BAA06663 BAC27792 BAE42462 EDL40755 | ||||||||
| RNA Seq Atlas | 18700 | ||||||||