Version 5.4
Mus musculus Gene: Hsd17b11
Summary
InnateDB Gene IDBG-185193.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hsd17b11
Gene Name hydroxysteroid (17-beta) dehydrogenase 11
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029311
Encoded Proteins
IDBP-185195
hydroxysteroid (17-beta) dehydrogenase 11
IDBP-400485
hydroxysteroid (17-beta) dehydrogenase 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198189:
Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:103989762-104021919
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000031251 ENSMUSP00000031251
ENSMUST00000119025 ENSMUSP00000113455
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0016229 steroid dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006694 steroid biosynthetic process
GO:0006710 androgen catabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005811 lipid particle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198189
View Gene Order
ENSBTAG00000006307
Not yet available
Cross-References
SwissProt Q9EQ06
TrEMBL
UniProt Splice Variant
Entrez Gene 114664
UniGene Mm.412946 Mm.46019 Mm.490893
RefSeq NM_053262
OMIM
CCDS CCDS19481
HPRD
IMGT
MGI ID MGI:2149821
MGI Symbol Hsd17b11
EMBL AF304306 AK049355 AK154803 AK155174 AK155202 AK155327 AK158327 AK170939 AY053570 BC038340
GenPept AAG41413 AAH38340 AAL14859 BAC33704 BAE32840 BAE33094 BAE33115 BAE33194 BAE34459 BAE42129
RNA Seq Atlas 114664

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca