Version 5.4
Mus musculus Gene: Alx3
Summary
InnateDB Gene IDBG-185347.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Alx3
Gene Name aristaless-like homeobox 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000014603
Encoded Proteins
IDBP-185349
aristaless-like homeobox 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene belongs to Group 1 of aristaless-like genes, which are characterized by the presence of an aristaless domain and a conserved paired-like homeodomain. The encoded protein acts as a transcriptional regulator. The protein plays a role in the development of craniofacial and appendicular skeleton and may have a role in pancreatic function. [provided by RefSeq, Apr 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:107595031-107605776
Strand Forward strand
Band F2.3
Transcripts
ENSMUST00000014747 ENSMUSP00000014747
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007389 pattern specification process
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0042981 regulation of apoptotic process
GO:0048704 embryonic skeletal system morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000156150
View Gene Order
ENSBTAG00000020966
Not yet available
Cross-References
SwissProt O70137
TrEMBL Q3UQX2
UniProt Splice Variant
Entrez Gene 11694
UniGene Mm.10112
RefSeq NM_007441
OMIM
CCDS CCDS17739
HPRD
IMGT
MGI ID MGI:1277097
MGI Symbol Alx3
EMBL AK142019 U96109
GenPept AAC15094 BAE24916
RNA Seq Atlas 11694

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca